- Archels questioned why MRI-guided ultrasound heating for non-invasive removal of malignant growths has not yet become a mainstream clinical commodity.  
- Kanzure proposed a bacterial-evolution platform for discovering potent nootropics: infect mouse brains with bacteria, harvest strains from high-performing animals, mutate them repeatedly, and re-test—initially for maze learning, but adaptable to sleep duration/quality and hippocampal size.  
- Discussion noted that hippocampal enlargement may not necessarily improve memory performance, and that post-mortem histology is the current method for measuring hippocampal volume in mice.  
- Shared links to post-mortem MRI and histology studies: primate hippocampal changes after death, comparative neuroanatomy of endangered species, and a 63-year-old mathematician’s brain autopsy.  
- Posted an interview with Gary Hudson of Oisin Biotechnologies covering their senescent-cell-clearance gene-therapy startup as an example of translational longevity research.  
- Highlighted the Dog Aging Project’s rapamycin trial for lifespan extension in companion dogs as an accessible longevity intervention study.  
- Noted that modafinil induces hepatic CYP3A4 metabolism, a consideration for drug-interaction and biohacking protocols.  
- Kanzure released a GitHub repository named “culture_shock” (https://github.com/kanzure/culture_shock) with unspecified but presumably relevant research or tooling.