- A newly identified SNP, rs2535913 in the DCAF4 gene, is associated with shorter leukocyte telomere length (p = 6.4 × 10⁻¹⁰) and lower DCAF4 expression; it has been added to the DIYH+ wiki “avoid” list for prospective genetic modifications.  
- Participants debated whether cataloging every deleterious SNP is practical, arguing instead for targeting whole signaling networks or selecting entire genomes from individuals with desired traits and subtractively editing them.  
- CRISPR/Cas9 was shown to restore dystrophin expression and improve pathology in a Duchenne muscular-dystrophy mouse model, demonstrating in-vivo muscle-specific gene editing as a viable therapeutic route.  
- Researchers achieved optogenetic control of DNA methylation by fusing DNMT3A or TET1 catalytic domains to light-inducible CRY2/CIB1 pairs, enabling reversible, blue-light–triggered silencing or activation of the Ascl1 proneural gene in neural stem cells.  
- A CMOS nanoelectrode array capable of all-electrical intracellular electrophysiological imaging at single-cell resolution was highlighted as a potential platform for high-throughput neural recording and stimulation.  
- The channel curated links to key reviews on induced-pluripotent-stem-cell (iPSC) reprogramming, synthetic modified-mRNA techniques, and epigenetic editing, underscoring their convergence with CRISPR tools for next-generation cell engineering.  
- A Nature news article summarizing the U.S. science advisers’ roadmap for genetically modified human embryos was circulated, framing the regulatory and ethical context for germline editing research.