• OpenWorm published a roadmap and comparative figure showing how training data from real C. elegans recordings align with outputs from their whole-organism simulation, marking a milestone for open-source whole-animal modeling.  
• Blockstream’s “Elements Confidential Assets” sidechain upgrade was highlighted as a working example of issuing cryptographically-blinded tokens on a public Bitcoin-compatible chain, enabling privacy-preserving asset issuance.  
• A CRISPR-based platform named CERES combines dCas9-KRAB and dCas9-p300 fusions to perform high-throughput gain- and loss-of-function epigenetic screens on native chromatin, offering a new tool for dissecting non-coding regulatory elements.  
• The iTango optogenetic system uses a dopamine- and blue-light-gated split-TEV protease to achieve temporal, cell-type-specific control of gene expression in dopaminergic circuits, providing a new method for circuit-level neuroscience.  
• The first live birth achieved via oocyte spindle transfer (“three-parent IVF”) was noted, along with the full genetic analysis published in Reproductive Biomedicine Online, demonstrating clinical feasibility for preventing mitochondrial disease.  
• A protocol for generating functional thymic organoids from FOXN1-reprogrammed fibroblasts was discussed as a potential cell-therapy route to restore age-related loss of T-cell production.  
• Participants debated the technical and philosophical limits of mind uploading: current connectomics cannot yet trace long-range neurites reliably, and vitrification-based cryonics may preserve structure without guaranteeing continuity of episodic memory.  
• A speculative identity-preservation scheme was proposed: continuously train uploaded brain models on a person’s live sensory stream and select the model whose responses best match the original—contingent on advanced AGI to perform the selection.