- Polyphasic sleep debate: participants questioned why no rigorous clinical studies exist on the “Uberman” schedule (six 20-min naps per day) despite decades of anecdotal claims; Buckminster Fuller reportedly maintained it for two years in 1943.  
- A 1990s Stampi study (cited but paper pay-walled) compared monophasic, biphasic and polyphasic sleep in sailors and found only a 12 % cognitive drop for nap-only sleep versus 30 % for monophasic deprivation.  
- Military and personal n-of-1 experiences were shared: 12 h awake / 6 h sleep on submarines, 12/12/36/12 port duty cycles, and a naturally converging 4.5 h night + 1.5 h afternoon “siesta” pattern.  
- Cost estimate for a formal 100-subject, month-long Uberman study with cognitive testing: ≈ $720 k; funding sources such as defense agencies or pharma were discussed.  
- Antibiotic-resistance analogy: one participant likened attempts to “solve” resistance to solving an entropy shortage by hashing, arguing bacterial evolution is inevitable.  
- Open-source microbiology links: “Strategies for culture of ‘unculturable’ bacteria” (Wiley review), a microbial-growth modeling PDF from Indiana University, and the suggestion to use viral vectors to deliver metabolism genes enabling growth on standard media.  
- Genome-editing note: preprint on “Enhancing Multiplex Genome Editing by Natural Transformation (MuGENT)” via ssDNA-exonuclease knockouts was circulated.  
- Neuro-tech references: 2013 DREADD chemogenetics short-course slides for remote control of cellular signaling, and a new Neuron paper on mnemonic-training-induced fMRI network changes underlying superior memory.  
- BioViva longevity-survey follow-up: invitees were offered a call with CEO Liz Parrish, CSO Avi Roy and CMO Jason Williams to discuss early-clinic access and trial design.  
- Atmospheric water harvesting: MIT MOF device that extracts potable water from desert air at 20–30 % relative humidity was highlighted.