- MIT’s Technology Licensing Office publicly lists its IP portfolio online, including an RNA-guided endonuclease DNA-assembly method (http://tlo.mit.edu/technologies/method-rna-guided-endonuclease-based-dna-assembly).  
- GP-write/HGP-write roadmap proposes phased pilot projects starting with ~1 % of the human genome and explicitly raises the idea of “designer chromosomes” that could carry entire metabolic pathways, e.g., genes to make a prototrophic human cell.  
- Keoni (Keoni Gandall) is offering 500 free 1.8 kb DNA fragments per month for four months under the OpenMTA license, followed by a 10 k-fragment order; channel members are the only ones with combined bio/electronics skills and debugging gear to test the boards.  
- Discussion of atherosclerosis pathogenesis: oxidized-lipid–laden macrophages become senescent “foam cells” that secrete NF-κB–driven SASP cytokines; NAMPT and Nrf2 are highlighted as key regulators of glutathione-mediated ROS control.  
- A transparent digital-microfluidic device fabricated from etched ITO foil was shared as a DIY lab-on-chip platform (YouTube link: https://www.youtube.com/watch?v=Rk_TbNyZdDg).  
- Public-opinion data: two-thirds of Americans approve of CRISPR gene editing to treat disease (Verge article and Hacker News thread referenced).  
- “Network of independent biospaces” mailing list is circulating an offer of free DNA synthesis; channel members debate how to fund further hardware development without traditional donation drives.  
- Side topics include coffee-resistance reset protocols, Taobao ordering in Chinese for lab hardware, and Bitcoin’s academic pedigree (Hacker News item 15134670).