- Allergan’s patent-transfer to the Saint Regis Mohawk Tribe is discussed as a new legal tactic that exploits tribal sovereign immunity to shield drug patents from USPTO inter partes review, with precedent from the University of Florida’s successful Eleventh-Amendment defense.  
- A deep-learning paper by Michal Kosinski is highlighted, claiming 80–90 % accuracy in inferring sexual orientation from facial photographs; links to the OSF preprint and Kosinski’s earlier warnings about psychometric profiling in political campaigns are provided.  
- Senolytic compounds beyond the canonical dasatinib/quercetin combination are debated; candidates include fisetin, FOXO4-DRI, piperlongumine, navitoclax, venetoclax, sulforaphane, and general BCL-2-family inhibitors, with a reference list at diyhpl.us/~bryan/papers2/longevity/2017-04-11-senolytics.txt.  
- Commercial DNA data-storage timelines are scrutinized: investors want a 5-year path to cost-competitive exabyte-level storage, prompting discussion of write-speed targets (e.g., 1 GB s⁻¹), required micro-valve counts, and centralized “data-dump” facilities fed by reusable hard drives.  
- Open-source DNA storage software is shared: the Helix.works “helix-dnadrive” library on GitHub and the MoSS (Molecular Storage System) white-paper at openmoss.org/docs/MoSS.pdf are flagged for review before upcoming meetings.  
- Twist Bioscience’s synthesis method is questioned; speculation centers on whether they employ inkjet-based oligonucleotide printing.  
- A call for new senolytics from an unnamed “high-level research initiative” is met with skepticism and a request for measurable in-vivo senescence assays.