• A free lecture series on cybernetics and transhumanist issues is hosted at https://www.cyberliving.uk/lectures/; the videos are listed in reverse chronological order and focus on practical problems rather than formal methods.

• The channel’s current research focus is on DNA synthesis; kanzure reported taking ~30 000 words of notes during a full-day SRC/IARPA workshop on the topic (https://www.src.org/program/grc/semisynbio/).

• Randall Hughes (Ellington Lab, UT Austin) and Bill Peck (Twist Bioscience) were highlighted as key figures; Peck’s background includes nanofluidics, turbulence physics, and two generations of Agilent high-density microarray manufacturing platforms.

• nmz787 introduced “normal mode resonance” (https://en.wikipedia.org/wiki/Normal_mode) as a technique for analyzing protein conformational changes, likening it to resonant vibrational patterns that can be excited in biological structures.

• Discussion of open-science infrastructure included the desire for a local, searchable copy of Sci-Hub to automate literature searches and escape “intellectually inbred” search-result loops.

• Practical materials question: whether sufficiently pure silicon dioxide can be produced from common sand; jrayhawk noted that while gas-centrifuge purification of glass is possible, mining high-purity quartz remains far cheaper.