- Low-energy electron-beam lithography can now pattern 15 nm lines at 60 nm pitch in 60 nm-thick ZEP-520 resist, with resolution limited mainly by electron forward scattering in thicker resist layers.  
- Two new CRISPR tools were spotlighted: (1) the adenosine base editor ABE7.10, which converts A•T→G•C without double-strand breaks at ~50 % efficiency and ≥99.9 % purity in human cells, and (2) the REPAIR system, which fuses catalytically dead Cas13 to ADAR2 for programmable A-to-I RNA editing in mammalian transcripts.  
- A Reddit/Hacker-News debate questioned the validity of a recent stem-cell anti-aging study, with critics citing lack of dose-response and inconsistent benefits, while defenders argued that not all “breakthrough” posts are hype.  
- DNA strand-displacement computing was discussed with key references: Soloveichik et al.’s PNAS paper “DNA as a universal substrate for chemical kinetics” and a Chemical Science report on a DNA-hairpin/DNAzyme full adder.  
- Participants brainstormed low-capital biotech projects—electrochemical DNA synthesis with an Arduino, open-source directed-evolution platforms, and DNA data storage—as potential near-term income opportunities under $5–20 k budgets, though DNA storage was framed more as a hobby than a revenue source.  
- Market-research industry practices were dismissed as “lemon market” plagiarism; Fermi estimation was recommended instead for sizing emerging tech sectors.  
- RTL-SDR experiment ideas for the NooElec E4000 dongle were shared, including Bitcoin-over-satellite reception and DARPA SDR hack-fest notes.