- The Zcash Foundation announced “Powers of Tau,” the world’s largest multi-party computation ceremony, intended to generate secure public parameters for the Zcash cryptocurrency.  
- GP-Write organizers are still favoring Twist Bioscience for DNA synthesis rather than designing for 5–10-year capacity and technique roadmaps, prompting concern about long-term scalability.  
- A Lightning Network integration-test tracker was shared (https://cdecker.github.io/lightning-integration/) to monitor interoperability among LN implementations.  
- CaptHindsight highlighted a Physical Review X paper describing “Rotation-Induced Macromolecular Spooling of DNA,” a method that uses rotational flow to align and manipulate long DNA molecules—nicknamed the “spaghetti-twist” technique.  
- Discussion of open-source micro/nanofluidic reagent loading: nmz787 emphasized the practical bottleneck of loading enzymes or other heat-sensitive reagents into microfabricated devices after fabrication.  
- Piezoelectric inkjet printheads were proposed as low-heat, off-the-shelf picoliter dispensers, but vendors keep drive-waveform specs under NDAs, forcing reverse engineering of commercial printers.  
- Heath circulated a Journal of Alzheimer’s Disease article proposing microbial (viral and bacterial) involvement in Alzheimer’s pathogenesis, linked via a ScienceAlert summary.  
- Fenn critiqued simplistic “culture fragmentation” narratives, asking for deeper future projections in light of algorithmically generated children’s content on YouTube.  
- Adlai and kanzure briefly debated time-management for reading technical papers, with kanzure asserting that “making the time” is the only viable strategy.