- A Medium post documents a self-experimenter’s one-month follow-up after injecting an “experimental genetic therapy” aimed at HIV; participants debate whether to call it a “treatment,” “protocol,” or simply an “injection” to avoid FDA scrutiny.  
- Safety discussion centers on the need to document risk analysis *before* administration rather than after the fact, with skepticism voiced about the lack of convincing evidence in the reported results.  
- Bryan Bishop adds two new wiki pages: one covering dCas13a for mRNA binding in gene-editing applications, and another summarizing 2017 iGEM projects.  
- A new Science paper, “Multiplex recording of cellular events over time on CRISPR biological tape,” is highlighted; a full-text PDF is mirrored at diyhpl.us.  
- A PLOS Biology article on rapid (<30 s) nucleic-acid purification from plants, animals, and microbes is flagged as a promising technique for field or DIY biology.  
- Philosophical exchange contrasts a desire to live 200 years while looking 20 and then die with the counter-vision of open-ended 200-trillion-year life extension.  
- Participants note sloppy terminology around “organic,” “human,” “mechanical,” and “robot,” cautioning that rigid definitions could rule out even routine dental work.