- CRISPR/Cas9 is now being used to delete entire chromosomes, with three recent papers cited: targeted chromosome elimination, megabase-scale deletions to create a fully haploid human cell line, and a general protocol for whole-chromosome removal.  
- A $150 transmission electron microscope (TEM) was spotted at a Texas auction; it was serviced until 2017 and includes a glass sample cover, prompting discussion about its suitability for DIY or low-cost lab use.  
- A critical Coinbase smart-contract bug was disclosed on HackerOne that credited ETH deposits even when the underlying contract execution failed, highlighting ongoing DeFi security issues.  
- A new on-chain heuristic for detecting covert ASICBoost in Bitcoin mining was published at pdaian.com, offering a potential tool for transparency in mining centralization debates.  
- The open-source Godot game engine was recommended as a non-Unity alternative for 3D/2D development, aligning with open-source transhumanist tool preferences.  
- BRL-CAD path configuration problems were reported: the build system ignores the BRLCAD_PATH environment variable and hard-codes incorrect installation directories, prompting a bug report.  
- Community brainstorming included tongue-in-cheek proposals like genetically engineering bees to produce maple-flavored honey, illustrating the channel’s blend of humor and speculative bioengineering.  
- Practical lab-safety questions were raised about preferred brands or designs for Biohazard Level 2 and 3 enclosures, seeking field-tested recommendations from DIY biolab operators.