- Youthereum.io is planning to sell transgenic pets with inducible OSKM (Yamanaka) genes for partial cellular reprogramming, using doxycycline as the trigger, and is collaborating with Dr. Vadim Gladyshev at Harvard to measure methylation-clock and other rejuvenation effects in OSKM mice and naked-mole-rat models.  
- Channel participants debated the ethics and terminology of human cloning, distinguishing “phenoclones” or “e-clones” (edited clones) from natural clones, noting that even identical twins show epigenetic and phenotypic variation.  
- A discussion arose about human gestation length: extrapolating from primate data suggests human pregnancy should last 2–3× longer, constrained by pelvic size; proposals included selecting for premie-survival mutations or engineering wider pelvises to allow longer gestation.  
- nmz787 offered to purchase 40–80 acres of buildable Oregon land near Portland (~$1–2 M) or a 255-acre river peninsula 2 hours away for $470 k as a potential transhumanist commune site.  
- kanzure shared a TechCrunch article on a fully 3-D-printed three-axis tourbillon watch movement, highlighting advances in desktop precision manufacturing.  
- lewl announced completion of introductory TensorFlow tutorials and posted the GitHub repo github.com/lewlking for review.  
- ClampFISH, an exponential RNA-FISH amplification technique, received an updated preprint with protocols and oligo tables (bioRxiv 222794).  
- Amazon’s mailed-HDD “Snowball” service remains the cheapest bulk-data export option, beating Google and Microsoft equivalents according to current price checks.