• A synthetic hairpin-shaped DNA-binding molecule that recruits programmable histone acetyltransferases was discussed as a new route to locus-specific epigenome editing; the reference DOI could not be resolved, but the concept was archived on the diyhpl.us wiki under “gene-editing”.  
• CRISPR Therapeutics’ first in-human gene-editing trial was placed on clinical hold by the FDA, prompting renewed debate on regulatory risk and safety standards for CRISPR-based therapies.  
• A STAT News article was circulated in which the father of a boy treated with Solid Biosciences’ Duchenne muscular-dystrophy gene-therapy vector reports functional improvements (e.g., throwing a softball), highlighting early patient-level evidence for systemic AAV gene transfer.  
• Coverage of Aaron Traywick’s death framed DIY biohacking’s image problem; participants linked the incident to broader questions of safety culture, public perception, and responsible innovation in citizen science.  
• Elephants’ cancer resistance attributed to multiple p53 copies was cited as a concrete example of how copy-number variation in tumor-suppressor genes could inform human enhancement strategies.  
• Over 100 common genetic variants have now been associated with IQ, jointly explaining ~5.2 % of population variance—an order-of-magnitude jump from the first credible hits reported only a year earlier.  
• A Science paper introduced “ultrafast” genetically encoded dopamine sensors enabling millisecond-resolved imaging of dopamine dynamics in behaving animals, opening new avenues for closed-loop neuromodulation research.  
• CellTag Indexing, a barcode-based multiplexing method for single-cell lineage tracing, was highlighted as a scalable tool for mapping developmental trajectories and clonal dynamics.  
• Fermilab’s 6-σ excess of electron antineutrinos over short-baseline expectations was shared as possible evidence for a new fundamental particle beyond the Standard Model, illustrating how frontier physics can inform speculative transhumanist scenarios.  
• Links to the Second International Summit on Human Genome Editing (Hong Kong, 27–29 Nov 2018) and to Open Quantum Safe’s post-quantum cryptography library (liboqs + OpenSSL fork) were distributed, underscoring the channel’s dual focus on bio-convergence and future-proof security.