- The GWAS Catalog released ~800 new genetic associations tied to intelligence, cardiovascular disease, and major depression, plus summary statistics for eye diseases and clostridium infection in multiple-myeloma patients.  
- A new biorxiv preprint demonstrates robust genome editing in C. elegans using short ssDNA and long, partially ssDNA donors, offering an alternative to traditional plasmid-based homology repair.  
- Boyden Lab posted a theoretical framework for single-molecule protein sequencing via weak-binding spectra, potentially extending next-gen sequencing from DNA to the proteome.  
- A modular dCas9-SunTag DNMT3A epigenome-editing system is reported to overcome the widespread off-target methylation seen with direct dCas9-DNMT3A fusions, improving locus-specific epigenetic control.  
- An updated landscape of emerging DNA-synthesis companies lists at least four new enzymatic platforms (AnsaBio, Molecular Assemblies, Nuclera, DNA Script) alongside older chemistries, tracked at calinplesa.com/dna-synthesis-companies.  
- Allen Cell Institute released an interactive “Visual Guide to Human Cells” with high-resolution 3-D images and segmentation data for major cell types.  
- Researchers converted red fluorescent protein into cross-linked biopolymer fibers via enzymatic crosslinking, demonstrating a route to fluorescent biomaterials.  
- A PCR-free protocol for seamless DNA assembly is described that directly prepares Cas9 ribonucleoprotein from E. coli, eliminating plasmid cloning steps.  
- Discussion of blood-substitute availability noted that Fluosol-DA (perfluorocarbon emulsion) remains the only FDA-approved oxygen therapeutic, while hemoglobin-based products have not reached approval; prior DARPA-funded work on ex-vivo cultured human RBCs from cord-blood stem cells appears to have stalled or gone un-commercialized.  
- A high-speed, industrial SLA 3-D printer using strong, relatively affordable resins was shared (Carbon3D-style continuous liquid interface), with technical data sheet linked.