• A paper on the “photo-taking-impairment effect” (Forget in a Flash) was shared, prompting discussion of a possible workaround: fusing chroma from visible-light images with luminance data from UV or IR flashes to reduce the memory-disrupting impact of visible-light camera flashes.

• Eroom’s Law—the observation that drug-discovery productivity is declining despite advancing technology—was introduced; participants questioned whether the trend persists after normalizing for the actual tools available in an average biotech lab at each point in time.

• A ResearchGate link to “The Short History of Science: the long path to the union of metaphysics and empiricism” was posted, framing the evolution of scientific method and its philosophical underpinnings.

• Genomic privacy was highlighted via a tweet noting that genomic data can only be “de-identified,” not truly anonymized, because future data aggregation will almost certainly enable re-identification.

• Leptin-based interventions were discussed: a 1997 PNAS mouse study on long-term peripheral and central leptin infusion and a 2004 JAMA clinical trial in humans, both underscoring the problem of leptin resistance in obesity treatment.

• A new scalable, multiplexed assay for decoding receptor–ligand interactions (bioRxiv preprint 358739) was circulated as a potential tool for accelerating ligand-discovery campaigns.

• An outsider asked whether the channel tolerates promotion of an anti-aging nonprofit; the response was strongly negative, with the assertion that nonprofit status itself signals “defective thinking” that likely infects other activities.