- Bitcoin’s environmental impact was debated: participants questioned whether its ~1 % share of global electricity use is unethical, and maaku argued most mining relies on otherwise-wasted renewable or surplus baseload power rather than carbon-intensive generation.  
- A satirical “Taboo Trades” website (http://www.tabootrades.com/veggie/) was shared, illustrating tongue-in-cheek markets for offsetting personal carbon or lifestyle choices.  
- Beta-carotene safety for ex-smokers was discussed; evidence shows high-dose supplementation increases lung-cancer risk in heavy smokers, whereas dietary intake or moderate combined antioxidant use appears safe.  
- Anti-aging supplementation conversation covered metformin (prescription AMPK activator), berberine (OTC AMPK/Nrf2/NAD⁺ booster at 1500–2000 mg/day), nicotinamide riboside (Niagen, direct NAD⁺ precursor), and the experimental neuroprotective compound P7C3-s243.  
- Caloric restriction’s natural NAD⁺ elevation was noted, yet participants agreed exogenous NAD⁺ boosters may still benefit aging individuals already practicing CR.  
- A user with Marfan syndrome asked whether TGF-β inhibitors could outperform standard β-blockers and ARBs for preventing aortic complications; the channel found little existing biohacker or clinical discussion on this angle.  
- nmz787 showcased a custom high-voltage electroporation setup using an STM32F401 microcontroller to capture current/voltage transients via DMA-interleaved ADC channels, with live plotting code.  
- A Rigol DS1054Z oscilloscope Python control library (https://github.com/pklaus/ds1054z) was highlighted as a useful open-source tool for lab automation.  
- GlobalFoundries’ cancellation of all 7 nm node development was noted as a significant setback for advanced semiconductor scaling (Hacker News link shared).