- Discussion of the first CRISPR-edited human babies reported in China, with links to both the original Hacker News thread and a follow-up Atlantic article titled “15 Worrying Things About the CRISPR Babies Scandal.”  
- Josiah Zayner’s DIY-bio advocacy was highlighted via a LeapsMag piece framing genetic engineering as “the last great frontier of human freedom,” contrasted with an IEET/BuzzFeed critique arguing that unsupervised biohacking “is not wise.”  
- Butterfly Sciences’ GHRH-plasmid gene-therapy project for aging was detailed, including its patent (US8993316B2), a company blog post on project status, and recruitment criteria seeking “old and healthy jocks” willing to fund development.  
- Emphasis on manufacturing purity: clinical-grade plasmid preps for human use cost ~$700 k versus ~$10 k for research grade, driven by ultra-low endotoxin requirements; the absence of human Siglec-13 was cited as making humans 1,000× more sensitive to LPS contamination.  
- Security and infrastructure notes: a BinaryEdge report on worldwide hijacking of Kubernetes clusters was shared, alongside a cryptoservices blog post on undefined-behavior pitfalls in cryptographic code.