- A modular dCas9-SunTag DNMT3A epigenome-editing system is reported to overcome the widespread off-target effects seen in direct-fusion dCas9-DNMT3A constructs, offering more precise DNA methylation control.  
- Researchers engineered red fluorescent protein into a fiber via enzymatic cross-linking, demonstrating a new route to fluorescent biomaterials and bio-textiles.  
- A multidimensional screening campaign produced channelrhodopsin variants with larger photocurrents and an order-of-magnitude reduction in calcium and proton currents, improving optogenetic tools for neural control.  
- A Reddit concept proposes a $9 billion LEO “planetary ring” built with existing technology, sparking debate on orbital stability and construction logistics.  
- Posts on hardware-wallet security detail how side-channel and firmware attacks can extract private keys, emphasizing the need for rigorous verification of firmware sources.  
- The “Dropgang” article outlines an evolution of darknet markets toward decentralized, dead-drop-based logistics that minimize online traceability.  
- A review of failed 2018 cryptocurrency predictions catalogs 15 dead projects, offering a data-driven post-mortem on hype cycles and technical shortcomings.  
- An Electrum wallet phishing campaign is highlighted, showing how attackers used fake GitHub URLs to trick users into downloading malicious updates.