- Hachimoji DNA: Science paper reports an 8-letter synthetic genetic code (A,T,G,C plus B,Z,P,S) that can be replicated and transcribed by an engineered T7 RNA polymerase, expanding the biochemical alphabet for future synthetic-biology applications.  
- Evolv-R CRISPR tool: Addgene blog details a targeted-mutagenesis system that fuses an error-prone polymerase to a nicking Cas9, enabling localized diversification of specific genomic regions without double-strand breaks.  
- Single-cell RNA-seq critique: Diamond Age post highlights the statistical and technical challenges of detecting differential gene expression at single-cell resolution, emphasizing pitfalls in current analysis pipelines.  
- He Jiankui ethics paper censorship: The CRISPR Journal retracted Jiankui’s 2018 draft “Ethical Principles for Therapeutic Assisted Reproductive Technologies”; kanzure archived the PDF and criticized the retraction as academic censorship of dissenting bioethics views.  
- DIY gene-editing resource: kanzure pointed to an extensive wiki (diyhpl.us/wiki/gene-editing) covering techniques, tools, and safety considerations for open-source bioengineering.  
- Ice lithography: nmz787 shared a Harvard paper on using frozen water as a clean, residue-free resist for sub-10 nm scanning-probe nanofabrication, offering a low-contamination route to nano-device prototyping.  
- Bodyhacking con transcript: gnusha committed a transcript of Brian Bushway’s talk on sensory-substitution and human augmentation, expanding the open archive of DIY-transhumanist conference content.