- Boise State researchers are combining super-resolution microscopy with DNA-origami scaffolds that carry “address tethers” to localize single dye molecules at known CCD/CMOS coordinates, enabling detection of individual photons and pushing the limits of optical super-resolution.  
- A long debate questions whether coherent-optical or holographic principles can explain biological information processing; one side argues that life’s reliance on dissipative, error-generating copying mechanisms makes coherent effects irrelevant, while the other claims deeper quantum or post-quantum frameworks may still apply.  
- The conversation repeatedly contrasts classical, dissipative cellular homeostasis (stable attractors, bistable flip-flops, food/heat requirements) with the unitary, non-copying nature of quantum computation, concluding that genetics operates in a classical-probability regime even if quantum chemistry underlies molecular interactions.  
- Participants cite the Poinsot construction, nonlinear optical amplification, and elastic vs. inelastic light scattering as analogies, but ultimately treat them as illustrative rather than explanatory for biology.  
- Kanzure links to PLOS ONE and Neuron papers showing that over-expressing CaMKII can enhance memory (creating “Doogie” mice) or erase recalled memories, highlighting CaMKII’s role as a signaling hub for NMDA-receptor–mediated plasticity.  
- Off-target CRISPR edits are discussed as a major barrier; the “unsequencable dark matter” on chromosomes is identified as the key missing data needed to solve specificity, with routine sequencing handling everything else.  
- Wilbanks tweets warn that biologists risk repeating the “PDP line computer” mistake—focusing on academic resource allocation while a personal-computer-scale bio revolution (cheap, distributed, consumer-grade tools) takes off unnoticed.