- A review paper in Frontiers in Neuroinformatics estimates that an accurate whole-brain simulation would require on the order of 10²⁴ FLOPS (yottaflop-scale) to capture ~90 B neurons, ~1,000 T synapses, ~90 B glial cells, ~450 B vascular end-feet, and molecular-level dynamics (≈1,000 reactions per molecule per second).  
- The same paper provides a concise “brief history of simulation neuroscience,” offering a high-level roadmap of past and current large-scale brain-modeling efforts.  
- Cyagen’s “TurboKnockout®” service was highlighted as an example of how CRISPR-based, fast-turnaround genetically engineered mouse/rat models are now commercially available, signaling mainstream adoption of advanced genome-editing tools.  
- Community member juri_ announced development of open-source software aimed at improving the fidelity of bioprinted tissues, underscoring ongoing DIY/open efforts to enhance biofabrication quality.  
- Links to applied genomics resources were shared, including the Quinlan Lab’s GitHub repository “applied-computational-genomics” and the BioStar Handbook, both intended as practical guides for researchers working with sequencing data and variant interpretation.  
- The COMBINE 2019 meeting (co.mbine.org/events/COMBINE_2019) was noted as a key upcoming gathering for standards and tools in computational modeling of biological networks, with at least one channel participant planning to attend.