- Participants debated the relative safety of vaping versus smoking, with one contributor arguing that even 15 years of e-cigarette use has produced no documented deaths, while 24 years of smoking carries well-known carcinogenic risks.  
- A DIY nicotine-delivery concept was proposed: use pharmacy-grade ultrasonic humidifiers to create a pure water mist and separately volatilize pharmaceutical-grade nicotine, minimizing unknown combustion by-products.  
- The psychological components of smoking addiction—throat hit, visible exhalation, and flavor—were identified as critical design constraints for any effective harm-reduction technology.  
- The 2019 U.S. “honey cut” disaster (vitamin E acetate in illicit THC cartridges) was cited as a cautionary tale about opaque supply chains and the need for rigorous analytical chemistry (GC/MS) to detect adulterants.  
- Regulatory gaps were highlighted: even in the EU, upcoming labeling requirements for finished e-liquids do not extend to the unregulated food-grade flavor concentrates that manufacturers mix into them.  
- A consensus emerged that the safest path for current smokers is unflavored, pharmaceutical-grade nicotine delivered via the simplest possible hardware, followed by complete cessation.