• A 2010 randomized trial (IOVS) demonstrated that deliberately defocusing lenses can act as “resistance training” for ciliary muscles and slow myopia progression, though participants questioned the achievable diopter reversal and long-term durability of the effect.

• nmz787 is constructing a 10-inch-ID sewer-pipe vacuum chamber to vapor-deposit FDTS (perfluoro-decyl-trichloro-silane) onto nickel-plated drums for anti-stick imprint-lithography, with surface activation via RF plasma or hot H₂O₂ identified as the current technical bottleneck.

• Participants highlighted severe legal constraints on hobbyist chemistry: in Texas and other states, possession of common glassware (two-neck flasks, condensers, Erlenmeyers, even coffee filters) can be prosecuted as drug paraphernalia unless the owner holds an ACS-accredited degree and meets hazmat/fire-code storage rules.

• The channel reviewed the 2018–2019 prison sentences handed to He Jiankui and collaborators for the CRISPR baby experiment, using the case to discuss the legal and career risks of unauthorized human germline engineering.

• Recent neuroscience literature (Nature 2018 GWAS, 2018–2019 stimulation studies) was summarized: large-scale UK Biobank imaging-genetics data now links common variants to brain structure, while electrical stimulation of lateral temporal cortex and perirhinal inputs, plus RNA-mediated “memory transfer” in Aplysia, show promise—but the latter lacks sequence-specificity controls.

• Enforcement anecdotes illustrated the hostile regulatory climate for DIY science: home labs can trigger multi-agency raids (fire, haz-mat, police) over petri dishes or “heat boxes”; unlicensed RF projects invite FCC/NSA fines and confiscation; and one hobbyist received a felony for building an Atmega8 satellite-TV decryption card, losing voting and travel rights.