- A new Nature paper on “In vivo RNA editing of point mutations via RNA-guided adenosine deaminases” was shared (https://www.nature.com/articles/s41592-019-0323-0) and added to the DIYH+ wiki gene-editing page.  
- Anders Sandberg’s upcoming book will devote three chapters to formalizing the lifecycle of space habitats and demonstrating positive growth rates for off-earth manufacturing; he is considering turning the material into an Oxford course with recorded lectures.  
- Discussion of open-source “machine ecology” concepts noted that while academics like Sandberg and Phil Metzger advocate for them, no major funders (e.g., Bezos, Musk) have publicly embraced the approach despite off-earth manufacturing rhetoric.  
- CubeSpawn, an open-source modular CNC/rapid-prototyping ecosystem, was highlighted as recently active and relevant to distributed manufacturing goals.  
- A GoFundMe campaign titled “Making a Live Dinosaur” (http://gofundme.com/f/making-a-live-dinosaur) was circulated as a real-world “Jurassic Park” effort.  
- kanzure argued that molecular biology—especially protein engineering and ribosome reprogramming—offers the fastest route to true nanofactories, rather than relying solely on DNA origami or top-down MEMS approaches.  
- Participants brainstormed a low-cost, mass-producible presymptomatic marker for coronavirus infection that would trigger a visible human biomarker without needing full PCR or therapeutic intervention.  
- MIT Media Lab reportedly banned the channel after objecting to a live transcript that misquoted a speaker as saying “Libra will be managed by vampires” instead of “managed by Facebook.”  
- A lengthy exchange evaluated whether the peptide-like nootropic Noopept could exacerbate autoimmune kidney disease (IgA nephropathy); consensus was that evidence is weak, the compound behaves more like a small-molecule drug, and safer ADD alternatives such as modafinil should be prioritized.