- Coronavirus-related supply-chain delays: JLCPCB has halted assembly services entirely, and other board houses are quoting 2–5 extra days for bare-PCB and assembly jobs.  
- Open-source geometric-modeling discussion: kanzure shared notes on OpenCASCADE (used by FreeCAD) and his own experimental “lolcad” kernel; lsneff and juri_ debated the speed and resolution limits of CSG versus implicit/f-rep kernels, with lsneff linking nTopology’s white-paper on implicit modeling advantages.  
- Focused Ion Beam (FIB) hardware offer: a fully functional Micrion 2500 FIB with four gas chemistries, full schematics and service docs is available for ~US $20 k (tweet via @nanographs).  
- DIY transhumanist wiki updates: new transcripts from Stanford Blockchain Conference 2020 covering transparent SNARKs, scalable RSA modulus generation, hardware-accelerated RSA, on-chain lending, TLS oracles, mixicles, and Prism/Streamlet consensus protocols.  
- Jango.bio press release: company is creating organoids aimed at “complete hormone restoration,” positioned as a regenerative-medicine approach to endocrine enhancement.  
- Neurostimulation thread: half-serious brainstorming about which brain region to “zap” to eliminate procrastination; jrayhawk argued procrastination is an adaptive catecholamine-upregulation strategy, while superkuh suggested mesolimbic dopaminergic targets.  
- Open-access paper on phi29 DNA polymerase engineering for XNA (xeno-nucleic acid) synthesis, highlighting directed-evolution work to expand the polymerase’s substrate scope.  
- Waste-to-food bioprocess: anaerobic digestion of human waste yields methane that fuels growth of protein- and lipid-rich bacterial biomass, described as “Vegemite-like” microbial goo (ScienceDirect article).