- Discussion of amino-acid-biased proteins: spider silk was cited as an example of a protein highly enriched in only a few amino acids, and prolamins (e.g., gliadin, zein) were identified as plant “storage” proteins rich in proline.  
- Query about amino-acid transport: participants asked whether all amino acids reach tissues solely via the bloodstream and lymph or if alternative distribution mechanisms exist.  
- Hypothesis of regional, historic differences in human amino-acid usage: the channel debated whether geographically distinct plant diets could have led to population-level differences in essential-amino-acid ratios in human proteins, versus human mobility smoothing out such variation.  
- Observation on dietary adaptation speed: it was argued that cultural dietary shifts (e.g., adding beans) are far faster evolutionary levers than waiting for germ-line mutations to rebalance amino-acid metabolism.  
- Brief note on branched-chain amino acids (BCAAs): leucine, isoleucine, and valine together constitute ~35 % of essential amino acids in muscle proteins and ~40 % of preformed amino acids required by mammals.  
- COVID-19 and ACE2 speculation: a tweet asking “Is it too soon to talk about ACE-2 mutant CRISPR babies?” prompted discussion that such edits would likely be futile because viral mutation would simply match the new receptor, and coronavirus is not an extinction-level threat.  
- Vaccine economics aside: participants complained that the hard part of vaccine development is not technical but pricing and profit considerations.  
- Hackaday link shared: EU VAT rule changes were highlighted as a new bureaucratic burden for small-scale hardware hackers and open-source developers.