• Reovirus is highlighted as a naturally oncolytic virus that preferentially infects and lyses cancer cells; 32 clinical trials are completed or underway, and a 2016 evidence-based review (PMC4918368) summarizes its therapeutic potential.

• Participants debate replacing the human immune system with a synthetic, photonically controlled version, drawing parallels to earlier proposals for electronically gated DNA polymerase systems and discussing security implications of “hooking your genetic code up to the internet.”

• A JACS paper (10.1021/jacs.9b11545) on a “multimachine communication network that mimics the adaptive immune response” is shared via Sci-Hub, alongside discussion of electrochemically directed DNA synthesis on chips (Nucleic Acids Research 2005) and the possibility of on-chip transfection reagents or stored stem cells for immune updates.

• Trehalose-based cryopreservation is examined in depth: nanoparticle and apatite-nanomaterial delivery systems achieve intracellular trehalose levels up to ~0.24 M, while vitrification-grade protocols use multi-molar cocktails (e.g., M22); desiccation tolerance via trehalose is also linked to potential advances in cryonics and long-term cell storage.

• Kanzure circulates a 2017 draft paper on “Electronic manipulation of polymerase for DNA synthesis,” noting the low toxicity of cordycepin and its potential antiviral properties; the conversation also covers phage display for antibody optimization and the historical shift from murine hybridomas to fully human antibody platforms.