- The Biostasis2020 livestream showcased Robert McIntyre’s aldehyde-stabilized cryopreservation and Greg Fahy’s first vitrified rabbit kidney, with talks on cryoprotectant toxicity, cytokine-storm research, and SEM images of vitrified brains (YouTube: https://www.youtube.com/watch?v=dwSF5dECa84).

- Participants outlined an open-source micro-EDM ecosystem: 1 W, ~100 V nanosecond-pulse power supplies, carbon-fiber electrodes down to ~6 µm, and a “self-drilled hole” trick (https://www.sciencedirect.com/science/article/abs/pii/S0924013604002596) to iteratively sharpen tips without re-mounting.

- A RepRap-style micro-EDM project was proposed to slash “vitamins” in 3-D printers by letting hobbyists EDM metal frames and precision parts, while MetalicaRap—an open selective-laser-melting printer for metals and glass—was noted as “largely self-printing” with a €10 k kit cost driven mainly by its high-vacuum pump.

- CBN Nano Technologies, inheriting patents from a stealth California startup once employing Ralph Merkle and Robert Freitas, received CAD $40 M to embed atomically precise markers (possibly nano-computers) in banknotes for anti-counterfeiting, prompting debate on feasibility and inspection logistics.

- Intel’s roadmap to atomically precise manufacturing (APM) is viewed as an incremental extension of atomic-layer deposition (ALD) and atomic-layer etching (ALE) rather than Drexlerian mechanosynthesis, which is seen as hard to parallelize; the only confirmed mechanosynthesis experiments involve silicon, not carbon.

- The Foresight Institute’s “Productive Nanosystems” roadmap (https://foresight.org/roadmaps) was cited as a historical artifact, with consensus that the field “died” after splitting from Drexler and failing to produce reproducible results that attract funding.

- Schafmeister’s spiroligomer chemistry remains active, now funded by the DoD for sarin-degrading catalysts, and was suggested as a candidate for medical or even Bitcoin-wallet applications.

- Open-source AFM paths were shared, including a Chinese educational design (Instructables PDF: https://cdn.instructables.com/ORIG/F48/7YYU/HUMS9U64/F487YYUHUMS9U64.pdf) and the Stromlinet-Nano kit (https://www.stromlinet-nano.com/).

- Automated liquid-handling and remote-controlled micro-manipulators (piezo disk nanopositioners, dataglove interfaces) were framed as stepping-stones toward quasi-self-replicating supply chains where gig-economy workers assemble prototypes online before full automation.

- Discussion highlighted the scarcity of open-source geometry kernels (Parasolid, ACIS, OpenCASCADE, SolveSpace) and the difficulty of writing new ones, with Rust/WASM portability noted as a way to avoid “being stuck with browser-only CAD.”