- A discussion on using EEG-based sleep monitoring to log sleep quality and potentially create a feedback loop with metronomic ticking timed to brainwave speed to enhance deep sleep stages, referencing a 2013 study on reinforcing rhythms in the sleeping brain with a computerized metronome.  
- A debate on the feasibility of DIY COVID-19 vaccines, with yashgaroth dismissing the idea that the Moderna vaccine is "simple" to replicate, while noting that sourcing peptides for the Radvac protocol is relatively easier but lacks efficacy data.  
- Clarification on peptide sourcing bottlenecks: 4–5 week lead times are typical due to manufacturing (including purification) and queue delays, with expedited service offering minimal improvement; legal risks for labs are low, but they may refuse sales to individuals ordering Radvac sequences.  
- A brief exchange on the hardness of sci-fi in *The Expanse*, praised as the closest to "hard sci-fi" on TV in decades, despite liberties with propulsion systems.  
- A tangent on historical vaccine development, including Pasteur’s accidental discovery of chicken cholera immunity and the misconception that UV exposure was used in early rabies vaccine preparation.