- Metformin’s off-label use for cognitive enhancement and longevity was debated; participants noted its neurogenic effects in a 2012 study yet questioned long-term safety and the lack of population-level IQ data in PubMed.  
- A practical discussion arose on legally obtaining prescription metformin without a doctor, with mention of UK rules allowing personal importation while forbidding foreign sales.  
- Commercial methane-to-protein technology (e.g., Calysta’s FeedKind) was highlighted as a solved, non-GMO process that turns $15/ton CH₄ into 60 % protein feed, though currently aimed at aquaculture rather than human food.  
- DIY BCI experimentation was described: a member molded molten polycaprolactone (PCL) in the ear canal to create custom-fit earphones for otoacoustic-emission measurements toward brain-computer-interface applications.  
- Links shared included an arXiv paper on fully automated manga translation (2012.14271), a LessWrong post warning about a faster-spreading European SARS-CoV-2 strain, Boston Dynamics’ Spot robot store, and a viral video of dancing robots.