- A pre-print on “Universal DNA methylation age across mammalian tissues” (biorxiv 2021.01.18.426733v1) was shared as a new cross-species epigenetic clock resource.  
- Discussion centered on a proposed blockchain whose proof-of-work would be molecular-dynamics simulations followed by physical synthesis and empirical validation of predicted molecules; the goal is to generate large public-domain chemical libraries without patent lock-up.  
- Core technical objection: tying “useful” scientific computation to consensus security creates misaligned incentives—miners could be paid for both honest blocks and for grinding on malicious forks, undermining double-spend resistance.  
- Reference materials cited: andytoshi’s 2014 “ASIC-FAQ” (download.wpsoftware.net/bitcoin/asic-faq.pdf) and Nick Szabo’s “Shelling Out” essay (nakamotoinstitute.org) were used to explain why proof-of-work must remain pure “proof-of-waste” to preserve incentive compatibility.  
- A Nature Communications paper on the tuatara’s dual mitochondrial genomes (s42003-020-01639-0) was linked as an example of complex genomic organization relevant to longevity research.  
- Longevity.Technology coverage of a start-up pursuing whole-body mitochondrial transfusion therapy was noted as a newly funded intervention in aging biology.  
- A Twitter thread lamented the absence of reputable physician networks offering evidence-based longevity and nootropic therapies; participants brainstormed a member-owned “Health+” cooperative model to solve the problem.