- A ten-year roadmap for a complete mouse connectome scan is being discussed; some participants argue the timeline is too conservative and favor accelerating the effort through better collaboration and tool development.  
- Janelia’s FIB-SEM Technology team (https://www.janelia.org/project-team/fib-sem-technology) is cited as already scaling volume-imaging techniques incrementally, suggesting incremental progress toward whole-brain connectomics.  
- Participants debate practical “biological backup” strategies: L29Ah proposes freezing a biopsy for DNA preservation, while others hint at simpler or “unspeakable” alternatives without elaboration.  
- DIY materials science links are shared, including YouTube tutorials on making superconductors (https://www.youtube.com/watch?v=RS7gyZJg5nc) and aerogel (https://www.youtube.com/watch?v=Y0HfmYBlF8g), indicating interest in low-cost, open-source fabrication methods.  
- The conversation highlights systemic bottlenecks in open science: limited author lists on papers and fragmented collaboration are seen as slowing progress on large-scale neuroimaging projects.