- A recent paper on a multi-component lifestyle intervention (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8064200/) was critiqued for lacking adherence data and for high variability in the control group; participants suggested that multiple baseline measurements would improve reliability.  
- Discussion highlighted the methodological and financial challenges of diet-based randomized controlled trials, with a curated list of paleo-diet RCTs and single-arm studies provided as references (https://scholar.google.com/scholar?q=wahls+diet+randomized+trial).  
- Interest was expressed in prioritizing rigorous outcome measures over specific interventions when evaluating lifestyle studies.  
- A Cell paper on a rare β1-adrenergic receptor mutation that significantly alters sleep/wake behavior was shared (https://www.cell.com/neuron/fulltext/S0896-6273(19)30652-X).  
- An arXiv preprint on using computational methods to solve archaeological puzzles was circulated (https://arxiv.org/abs/1812.10553).  
- A $15 million legal settlement for lost eggs and embryos prompted commentary on the need for more reliable cryostorage systems (Reddit thread: https://www.reddit.com/r/news/comments/nxfhni/15m_awarded_to_five_people_who_lost_eggs_embryos/).