- OpenAI’s private text-to-image diffusion models have reached “terrifyingly good” quality, according to a newly released arXiv paper (https://arxiv.org/abs/2112.10741), signaling a major leap in generative AI capabilities.  
- A community member asked for practical methods to mill small (≈1 mL) pharmaceutical granules into fine powder; consensus advice was to use either a rock-tumbler–style ball mill with steel bearings or a simple mortar and pestle, with the caveat that the process is loud.  
- Discussion confirmed that grinding slow-release methylphenidate (Ritalin) tablets converts them to an instant-release formulation, whereas prodrugs like lisdexamfetamine remain unaffected because their activation depends on enzymatic cleavage of the lysine moiety.  
- Archive.org’s public FAQ (https://help.archive.org/hc/en-us/articles/360014755952-Archive-org-Information) states they currently charge no upload fees and estimate long-term storage costs at ~$2 per gigabyte, prompting debate about the sustainability of hosting large, non-public “dark” data sets.  
- The “Zero to ASIC” course (https://www.zerotoasiccourse.com/) was shared as an open educational resource for learning to design and tape-out custom silicon, lowering barriers for hardware-oriented bio- and neuro-tech projects.  
- A link to the draft textbook “Intuitive Advanced Cryptography” (https://github.com/cryptosubtlety/intuitive-advanced-cryptography/raw/master/advancedcrypto.pdf) was circulated, offering an approachable yet rigorous guide to modern cryptographic primitives relevant to privacy-preserving health and AI systems.