- Foresight Institute published a “Longevity Technology Tree” report mapping R&D pathways for molecular machines, neurotechnology, computing, and space systems aimed at radical life-extension.  
- The 2021 PDF (linked) details technology-readiness levels and open research gaps for atomically precise manufacturing, nanomedicine, and brain–computer interfaces.  
- Discussion of genome-sequence backup sizes: a 300 GB personal DNA archive is attributed to raw short-read data rather than the final assembled genome, highlighting storage challenges in consumer genomics.  
- Mechanical-only computing systems built exclusively from rigid links and rotary joints were featured on Hacker News, prompting concern that pioneers like Merkle and Freitas have produced little visible progress in two decades.  
- Skepticism voiced about CBN (carbon-nitrogen-boron) nanotechnology claims, with participants comparing them to unfalsifiable conspiracy theories rather than rigorous science.