- A new 2021 “technology news” digest covering IRC-centric open-source projects, biohacking tools, and transhumanist developments was shared at https://www.ilmarilauhakangas.fi/irc_technology_news_from_the_second_half_of_2021/.

- Michael Nielsen tweeted a link to Adam Marblestone’s 2021 review “Bottleneck analysis for positional chemistry,” a 30-page PDF that maps the current state of atomic-precision manufacturing and nanotechnology roadmaps (https://web.mit.edu/amarbles/www/docs/Bottleneck_analysis_positional_chemistry.pdf).

- Participants noted that “vacuum mechanosynthesis” experiments—atomically precise fabrication in high vacuum—are reportedly being attempted “secretively in Canada by enthusiasts,” suggesting an underground hardware effort toward Drexlerian nanotech.

- A lightweight Unix IRC client named “ii” (https://en.wikipedia.org/wiki/Ii_(IRC_client)) was highlighted as a favorite minimal tool; an XMPP-to-IRC bridge written by a channel member (https://github.com/l29ah/hatexmpp) was also circulated.

- The nootropic racetam family was discussed for cognitive enhancement: webmeister began a self-experiment with aniracetam and considered stacking coluracetam, oxiracetam, and pramiracetam, while noting that phenylpiracetam was sold out.

- kanzure solicited private feedback on an early-stage “webcash” project at https://webcash.tech/, hinting at new monetary or incentive mechanisms relevant to open-source science funding.