- Mitrix Bio claims to reverse age-related energetic decline by transfusing lab-grown “young” mitochondria into the bloodstream; early animal and in-vitro tests reportedly show rejuvenation effects, and the company is exploring whether non-human mitochondria could be used to avoid supply constraints.  
- Participants discussed the feasibility of mitochondrial supplementation, noting that simple plasmid insertion already struggles with cellular uptake and questioning how whole organelles could be efficiently delivered; the cell-penetrating peptide Octoarginine (R8) was cited as a possible uptake enhancer via macropinocytosis.  
- A thought experiment asked how a person who memorizes a Bitcoin seed phrase could incentivize future emulators to run their entire preserved brain rather than simply extracting the key; the consensus was that economic or technical incentives are weak and benevolent overlords would be required.  
- DIY collective Four Thieves Vinegar demonstrated “This Card is an Abortion,” a business card impregnated with three doses of misoprostol that can be dissolved under the tongue, distributed at a hacker conference to circumvent abortion-pill access restrictions.  
- Supply-chain discussion revealed that most racetam nootropics have disappeared from Western vendors after China restricted precursor chemicals; users reported subjective cognitive benefits from piracetam (fluency, reduced caffeine jitters) but noted its unpleasant taste and possible dependence on adequate choline levels.  
- A PCB-design checklist compiled from “the school of hard knocks” was shared (github.com/azonenberg/pcb-checklist) to help open-hardware projects avoid common fabrication and reliability pitfalls.  
- Thermodynamic analysis of direct air capture cited a practical energy cost of ~250 kWh per tonne CO₂ (≈0.9 MJ/kg), prompting questions about the theoretical lower bound for concentrating CO₂ from 400 ppm ambient air.  
- Channel members debated monkeypox transmission data showing 97 % of UK cases in men who have sex with men, questioning public-health messaging that classifies it as “not an STD” despite predominant sexual transmission routes.