• A new pre-print, “EvoBind: in silico directed evolution of peptide binders with AlphaFold,” demonstrates using AlphaFold to computationally evolve high-affinity peptide binders, potentially accelerating drug and sensor development (https://www.biorxiv.org/content/10.1101/2022.07.23.501214v1).  
• A companion paper, “High-resolution de novo structure prediction from primary sequence,” claims near-atomic accuracy in predicting 3-D protein structures directly from amino-acid sequences without homology templates (https://www.biorxiv.org/content/10.1101/2022.07.21.500999v1).  
• Discussion surfaced the ethics and legality of short-selling biotech stocks while simultaneously lobbying the FDA to halt an Alzheimer’s drug trial—participants questioned whether such “alarm-ringing for profit” violates SEC rules.  
• A Tachikoma-inspired holonomic robot mod for Prusa 3-D printers was shared, with suggestions to upgrade to true omni-wheels for better mobility (tweet link: https://twitter.com/NHengist/status/1551149767237009410).  
• North End Makers in Seattle was praised for its large space, water-jet cutter, and resin printers, highlighting the continued growth of well-equipped community bio- and hardware labs.  
• DiceKeys—a physical, dice-based master-secret generator for password managers—was introduced, alongside comparisons to hardware password vaults like Mooltipass, OnlyKey, and Beamu (https://dicekeys.com/, https://www.beamu.io/, https://www.themooltipass.com/, https://onlykey.io/).  
• A $3–$4 BLE temperature/humidity sensor (tp357) was recommended for distributed environmental monitoring; quick calibration data showed ±0.3 °C repeatability across units (GitHub repo: https://github.com/pasky/tp357).  
• Peter Thiel’s recent interview on the dangers of unchecked technological progress was circulated for critique (https://unherd.com/2022/07/peter-thiel-on-the-dangers-of-progress/).