- A new stretchable, high-conductivity organic bioelectronic material was described: a PEG backbone threaded with sliding cyclodextrin rings, cross-linked with PEDOT:PSS, enabling photolithographic patterning down to cellular scale and demonstrated use for stable electromyography on octopus and single-nucleus neuromodulation (Science 2022, Zhenan Bao group).  
- Discussion of desktop oligonucleotide synthesizers noted that the $30 k Kilobaser system offers ~$0.50 / bp for 20–40-mer primers—costlier and little improved over 20- to 30-year-old ABI machines.  
- A proposed “reverse translation” workflow was outlined: use a ribosomal system with alternating codons and a mismatched aa-tRNA library to synthesize arbitrary proteins, then chemically convert the peptide back to DNA via solid-phase oligonucleotide chemistry; patents US20070087377A1 and US7923533B2 were cited as related.  
- Prime editing (search-and-replace genome editing) was introduced and questioned for its practical mechanism versus traditional Cas9 approaches.  
- An artificial restriction DNA cutter technique named “ARCUT” (chemical DNA editing) and a 2001 paper on self-replicating peptides were shared as additional molecular-biology tools.  
- Real-time satellite imagery remains elusive; Albedo’s product delivers images “within hours,” and an RTL-SDR attempt at live weather-sat reception was hindered by strong nearby FM interference.  
- Gen2 Starlink satellites were observed in person: 22 ft long, 2,755 lb (1,250 kg), with solar arrays nearly the width of the manufacturing building.