- A new Science paper (DOI: 10.1126/science.abl6422) reports that a single A-to-G mutation in the TKTL1 gene may underlie the greater neurogenesis and expanded neocortex observed in modern humans compared with other apes and Neanderthals; the finding was immediately flagged as something that should not be tested via ABE (adenine base editor) editing in non-human primates.

- Discussion of SecureDNA.org, a proposed system that uses “distributed oblivious pseudo-random function” techniques—possibly related to oblivious transfer or private information retrieval—to screen DNA synthesis orders without revealing the requested sequences, raising concerns about potential political misuse.

- A 73-minute YouTube talk titled “Deep Learning in Structural Biology and Protein Design: How, Where, and Why” (https://www.youtube.com/watch?v=UJGtwUFQKfs) was shared as a resource on applying deep learning to protein structure and design problems.

- The animated series “Pantheon,” which centers on brain uploading and mind emulation, was recommended as a well-executed exploration of transhumanist themes.

- Adenine base editors (ABEs) were noted as tools capable of precise A•T → G•C conversions, highlighting their importance in the expanding gene-editing toolbox.