- Nature reports that additional CRISPR babies may have been born since 2018 and that He Jiankui—now out of prison—is seeking private funding for a Duchenne-muscular-dystrophy gene-therapy project, raising the question of how to track science that operates outside traditional institutions.  
- Meta’s 7–65 B parameter LLaMA language models, trained solely on public data and claimed to outperform GPT-3 at 13 B parameters, had their weights leaked via torrent magnet links posted in a GitHub PR, prompting discussion on Hacker News about open-sourcing large models.  
- Tomorrow.bio advertises human cryopreservation “starting at just 31 € per month,” and participants joked about “cryo jihadists” while debating the cultural optics of the cryonics movement.  
- A mechanochemistry thread explored using ball-milling plus protein scaffolds or graphene flakes to template and stamp micro-diamond components, with cubic boron nitride tools suggested to prevent diamond adhesion.  
- Participants dissected the engineering barriers to replicating ASML’s EUV lithography machines, emphasizing multi-layer dielectric mirrors, precise laser-driven tin-droplet plasma sources, and the “1000-step” integration challenge; leaked ASML/Zeiss chamber photos and a YouTube walk-through were shared.  
- Balaji Srinivasan’s “network states” concept was linked to a Politico article suggesting it may influence Trump’s 2024 platform for futuristic charter cities, recalling earlier 2016 rumors that Balaji was considered for FDA head.  
- The channel archived a Twitter debate transcript on effective accelerationism (“e/acc”) between @bayeslord and Marc Andreessen, posted to the diyhplus wiki for reference.  
- Discussion of AI risk narratives noted a pattern in which successive “crises” (terrorism, climate, COVID, AI, germline editing) are invoked to justify centralized global governance, with reference to an OvercomingBias post.  
- A brief aside asked whether WikiLeaks would accept large AI model leaks, underscoring the community’s interest in radical transparency for frontier technologies.