- EUV lithography is dismissed as a 1950s-era concept; the channel argues that simple, low-cost nanofabrication routes are systematically starved of capital because funders favor expensive, complex projects, and technologists must redirect investment away from incumbents (citing Feynman’s 1959 talk).

- A brain-efficiency critique of digital compute claims that 20 W human-level cognition implies today’s computers are “doing it wrong”; Landauer’s limit and Tim Palmer’s *The Primacy of Doubt* are recommended for non-Boolean, entropy-utilizing computation paradigms.

- Updated Moravec/Kurzweil curves project that 3–13 A100-equivalent GPUs (≈10¹⁵ FLOPS) will reach the $1 000 price point around 2031, suggesting commodity human-level hardware within a decade if trends persist.

- The group debates whether the future of AI will be dominated by open, sub-human “good-enough” models that run on phones or by centralized foundation-model giants that gate-keep access; crypto-mining is judged to have driven little real fabrication innovation.

- Training LLaMA-65B is estimated to have cost ~$5 M in GPU-rental (2 048 V100s for 23 days), while the 7 GB LLaMA-7B model already runs on high-end phones, illustrating the rapid compression of deployment costs once training is amortized.

- Shared neuroscience resources include Numenta papers on thalamo-cortical loops and grid-cell frameworks, Swanson’s zoomable rat-brain flatmap, downloadable human connectomes from braingraph.org, and Nectome’s glutaraldehyde fixation protocol for preserving synaptic and extracellular-matrix memory traces.

- Memory-storage hypotheses discussed include Goult’s “meshcode” cytoskeletal model, Tsien’s “pattern-of-holes in perineuronal nets,” and extracellular sulfated-proteoglycan analog storage, suggesting multiple loci for long-term information.

- Historical proposals to breed animals for intelligence are reviewed, from Francis Galton’s 1865 observation that no species had been selected for general cognition, to 1950s “I.Q. Zoo” Skinnerian experiments and unintended aggression in high-yield chickens, framed against David Pearce’s “Abolitionist Project.”

- A 1959 speculation (via Freitas) suggests that inducing one extra mitotic division in embryonic cortical cells could double human neuron count from 9 to 18 billion, offering a simple route to cognitive enhancement.

- Participants lament the lack of interactive tools that overlay brain-network connectivity data on anatomical maps; static node-edge graphs lose spatial context, and they propose CSS/transparent-PNG overlays or Gephi-style queryable modules as solutions.