- A Johns Hopkins University group working on “organoid intelligence” is considered potentially transhumanism-friendly, prompting plans for in-person outreach and requests for introductions to other researchers in the field.  
- Boston-based researchers were highlighted, including a Tufts Levin Lab staff scientist (Sergeeva) who works on cortical organoids and had attended a prior Austin conference.  
- COMT-inhibitor pharmacology was discussed as a cognitive-enhancement strategy: Tolcapone crosses the blood–brain barrier but carries rare fatal hepatotoxicity, whereas Entacapone and Opicapone are peripherally restricted; the val158met polymorphism yields ~45 % enzyme-activity reduction and improved cognitive metrics at the cost of higher pain/anxiety.  
- A new pre-print describes a transgene-free, ex-utero human post-implantation embryo model derived solely from genetically unmodified naive pluripotent stem cells (bioRxiv 2023.06.14.544922).  
- The commercial trajectory of ex-utero lamb gestation research was noted to have moved to the company Vitara.  
- Links to two Twitter threads (Jacob Hanna and Vlad Bndk) were shared, presumably containing additional commentary on the embryo-model work.  
- Two technical wiki pages were circulated: one on “Digital control over reversibly composable units of matter” (apm.bplaced.net) and another on preparatory experimental R&D for “reprec and rechain” components (sci-nanotech.com).  
- SNPedia’s current editing policy came under scrutiny: users report IP-blacklisting errors that may effectively render the site read-only, raising questions about its continued openness.