• The Enhanced Games (enhanced.org) is floated as a performance-enhancement-legal “super-Olympics” with George Church listed as an advisor, prompting debate over whether it is a serious transhumanist project or mere buzzword marketing.  
• Nature’s 2023 report on Fanzor, a eukaryotic RNA-guided nuclease, is introduced as a new programmable gene-editing tool; the community prefers the acronym “OMEGA” for its branding appeal.  
• He Jiankui’s re-emergence on Twitter revives discussion of his 2019 DIY CRISPR baby experiment, the MIT Technology Review exposé, and its Bitcoin-based funding model.  
• Mark Wilcox’s “21e8” venture is dissected as a GPU-proof-of-work “computational data market,” but participants dismiss it as buzzword soup lacking code or concrete documentation.  
• A proposal emerges for cryptographic attestation of LLM outputs (prompt + response + signature) to let users verify results without re-running large models; no implementation yet exists.  
• Dominant Assurance Contracts (DACs) are analyzed as a mechanism to fund anti-aging research: an entrepreneur offers refund bonuses to early pledgers if the campaign fails, incentivizing even indifferent participants to push funding over the threshold.  
• Participants argue that DACs face practical limits at billion-dollar scales—current anti-aging startups already hold large VC reserves yet show unclear progress, suggesting the bottleneck is scientific and organizational rather than purely financial.  
• Nvidia’s reported shipment of ~200 000 H100 GPUs per quarter (~12 exaflops FP64) is noted to exceed the aggregate FP64 performance of the entire TOP500 supercomputer list.