- **SAM-e storage debate**: Participants discussed the need for better moisture barriers than standard ziploc bags for SAM-e (S-adenosyl-methionine), a methylation-related supplement; polyethylene’s high water permeability was highlighted, with aluminum or bentonite-filled polymers suggested as superior alternatives.  
- **Anesthesia awareness concern**: A statistic was shared that ~33 % of surgical patients under general anesthesia may be conscious but amnesic, while only ~0.2 % later recall the experience; the ethical question arose of whether undetected intra-operative awareness constitutes torture if memory is erased.  
- **EEG and physiological monitoring for consciousness**: It was proposed that EEG or heart-rate monitoring could potentially detect conscious awareness during surgery, though anesthetics directly modulate heart rate, complicating such detection.  
- **SAM-e personal experiment**: One user reported trying SAM-e once, experiencing only appetite suppression with no other cognitive or mood effects; cost was noted at roughly $1 per pill.  
- **Dopaminergic appetite suppression**: Appetite loss from SAM-e was attributed to its dopaminergic activity, with advice to deliberately maintain eating habits when using such compounds.