- Wi-Fi as imaging radar: a new arXiv pre-print (2301.00250) demonstrates centimeter-scale pose estimation through walls using only commodity 6-antenna Wi-Fi routers, reigniting debate on privacy implications versus camera-based systems.  
- Longevity pharmacology: user-provided hospital literature claims rapamycin/everolimus extend median mouse lifespan ~60 % on average, with some engineered strains showing up-to-440 % increases; discussion centered on mTOR inhibition, immune modulation, and the difficulty of translating such results to healthy humans.  
- Reproductive futurism links: shared articles on booming US commercial surrogacy driven by Chinese demand and on Silicon-Valley “pronatalist” movements framing high birth-rates as existential risk mitigation.  
- Critique of Effective Altruism optics: participants argued that EA’s public image is being harmed by association with FTX, “Big Yud,” and extreme long-termist spending, suggesting that moderating messaging could increase total funding and policy influence.  
- Food safety & heavy-metal accumulation: conversation reviewed bioaccumulation of lead and mercury in predator species (pigs, dogs, swordfish, chickens) and the trade-offs of eating high-trophic-level animals versus plant sources.  
- Peanut allergy policy reversal: a NEJM paper (DOI 10.1056/NEJMoa1414850) was cited showing early peanut introduction slashes allergy incidence, with side debate on peanut agglutenin’s inflammatory and carcinogenic potential.  
- 3-D organ printing gap: lament that promised cellular-scaffold transplants remain scarce; one participant noted personally working on the problem but lacking manpower.  
- Germline vs somatic anti-aging: off-hand remark that germline interventions may be technically easier and more fruitful than trying to repair accumulated somatic damage, though ethics committees were sarcastically acknowledged as a barrier.  
- Executive-function benchmarking: open question of how to design a competition or metric to identify humans at the extreme right tail of “general agency,” with candidates ranging from Olympic athletes to cult founders.