- Tor Project has introduced a client-side proof-of-work defense for onion services to mitigate DoS attacks, and Cloudflare’s Turnstile is already deploying similar PoW mechanisms.  
- braidpool is experimenting with FROST (Flexible Round-Optimized Schnorr Threshold) signatures to improve decentralized mining pool coordination.  
- A short discussion on AlphaFold availability noted that no one in the channel currently runs a local instance, though one participant plans to set one up.  
- Gershenfeld’s MIT group released a paper on “plate lattice kirigami,” a fabrication technique for creating complex 3-D mechanical metamaterials from 2-D sheets.  
- Several short peptide sequences (RELLEVVEPEVLQDSL, GVLMEVEEPEVLQDSL, etc.) were analyzed; GPT models suggested they likely form mixed α-helix/β-sheet structures and may participate in calcium or protein-binding roles, though definitive structure prediction remains unreliable.  
- Fluorine-terminated versus hydrogen-terminated diamondoid surfaces were debated for potential use in selective atomic-layer deposition (ALD) and corrosion resistance; polycrystalline diamond (PCD) surface chemistry papers were referenced.  
- A Nature paper on “Depletion of aneuploid cells in human embryos and gastruloids” was shared, highlighting mechanisms that purge chromosomally abnormal cells during early embryogenesis.  
- An arXiv preprint titled “Physical constraints in intracellular signaling: the cost of sending a bit” was linked, exploring thermodynamic limits on biological information transfer.