- First successful creation of humanized kidneys inside pigs: researchers used CRISPR to delete the pig genes SIX1 and SALL1, then injected human induced-pluripotent stem cells engineered to over-express MYCN and BCL2, allowing the human cells to out-compete pig cells and form organized mesonephros structures up to embryonic day 28.  
- The study, “Generation of a humanized mesonephros in pigs from induced pluripotent stem cells via embryo complementation,” was published in Cell Stem Cell and demonstrates a scalable route to growing transplantable human organs in large animals.  
- Ethical limit of 28 days was imposed to prevent human cell contribution to the pig brain or germline; participants questioned whether this cutoff is scientifically or politically motivated.  
- Lifespan.io article shared on combining metformin and galantamine as a potential therapy for sarcopenia, highlighting off-label drug repurposing for age-related muscle loss.  
- Discussion of China’s role in the research: the work was carried out at multiple CAS institutes and universities, prompting debate over international ethical standards versus China’s more permissive regulatory environment.