- A longevity-focused LLM released by GRG was tested and found to give “confidently wrong” answers, illustrating the pitfalls of training chat models on curated longevity literature.  
- Discussion of NAD+ precursors compared nicotinamide riboside (NR), niacin/niacinamide, and NMN; NR avoids flushing and different precursors appear to raise NAD+ in distinct tissues, prompting some vendors (e.g., NootropicsDepot) to sell blended “optiNAD” products.  
- Debate over young-blood transfusions concluded that mouse data show old blood dominates the phenotype; benefits seen in early studies likely arose from dilution rather than youthful factors, and plasmapheresis/saline dilution is safer and cheaper than full transfusion.  
- Participants explored practical self-experimentation logistics: buying research chemicals via a small company (business license, tax ID, SIC codes, non-residential address), sourcing CGMs on AliExpress for £43/2-week wear, and the possibility of banking one’s own young plasma for later autologous use.  
- Links shared included Bob’s Red Mill pre-ground flaxseed claimed to retain potency for one year, a PLoS ONE paper on great-ape sequence memory, and two blog posts arguing that quantum computing is “analog” rather than truly digital—critiqued as unclear and not worth reading.