- Mojo, the new high-performance Python-compatible language from Modular, is now available on macOS; a demo GIF shows it running the Llama-2 model at interactive speed.  
- Channel members expressed alarm over endocrine-disrupting chemicals and microplastics after reading Dr. Shanna Swan’s book, calling for increased toxicology funding and noting that compressing plastics into bulk forms at least reduces surface-area exposure.  
- The Interventions Testing Program (ITP) found that metformin, resveratrol, and nicotinamide riboside failed to extend lifespan in UM-HET3 mice, whereas rapamycin, telomerase-related treatments, and IGF-1/insulin-signaling genetic interventions did produce significant longevity gains.  
- LibreSilicon open-source semiconductor process documentation was praised as “pretty decent” but criticized for disorganization, spelling errors, and the sheer volume of process steps (a 200-step HKUST dry-process PDF was linked).  
- Luigi Cornaro, a 16th-century Venetian nobleman, was discussed as an early longevity experimenter who attributed his vigorous 98-year life to strict caloric restriction and coarse bread—an idea later critiqued by Nietzsche as confusing cause with metabolic predisposition.